the studi aim discuss relationship differ between myocardi perfus imag mpi use spect coronari angiographi ctca diagnosi coronari arteri diseas cad five hundr four case undergo mpi ctca were compar analyz includ fifti six patient undergo invas coronari angiographi same period among patient negat mpi result negat posit ctca occupi 847 153 respect among patient posit mpi posit negat ctca occupi 672 328 respect among patient negat ctca negat posit mpi occupi 944 56 respect among patient posit ctca posit negat mpi occupi 402 598 respect negat predict valu relat higher than posit predict valu posit ctca elimin predict abnorm haemodynam and signific differ sensit specif accuraci mpi ctca diagnos cad both mpi ctca have good diagnost perform cad they provid differ complementari inform diagnosi evalu cad name detect ischemia versus detect atherosclerosi which quit differ have definit intern link each other

Jian-ming Li

Ting Li

Rong-fang Shi

Li-ren Zhang

Comparative Analysis between SPECT Myocardial Perfusion Imaging and CT Coronary Angiography for Diagnosis of Coronary Artery Disease

malign transform tumor accompani profound chang normal neighbor tissu call tumor stroma the tumor stroma provid environ favor local tumor growth invas metastat spread nuclear imag pet spect measur biochem physiolog function human bodi oncolog pet spect particular use differenti tumor from postsurg chang radiat necrosi distinguish benign from malign lesion identifi optim site biopsi stage cancer monitor respons therapi indeed pet spect power proven diagnost imag modal display inform unobtain through other anatom imag mri when combin coregist data 18 fluorodeoxyglucos 18 fdg pet particular use howev 18 fdg targetspecif pet tracer this paper review tumor microenviron target oncolog imag angiogenesi invas hypoxia growth home also therapeut radiopharmaceut provid roadmap addit applic tumor imag therapi

Dinesh Shetty

Jae-Min Jeong

Hyunsuk Shim

Stroma Targeting Nuclear Imaging and Radiopharmaceuticals

radiotherapi play import role treatment thorac cancer accurat diagnosi essenti correct perform curat radiotherapi tumor delin also import prevent geograph miss radiotherapi plan current plan base comput tomographi imag when radiat oncologist manual contour tumor practic often induc interobserv variabl f18 fluorodeoxyglucos positron emiss tomographi fdgpet has been report enabl accur stage detect tumor extens sever thorac cancer lung cancer esophag cancer fdgpet imag has mani potenti advantag radiotherapi plan cancer becaus can add biolog inform convent anatom imag decreas interobserv variabl fdgpet improv radiotherapi volum enabl dose escal without caus sever side effect especi lung cancer patient the main advantag fdgpet esophag cancer patient detect unrecogn lymph node distal metastas howev automat delin fdgpet still controversi tumor despit initi expect review role fdgpet radiotherapi thorac cancer includ lung cancer esophag cancer

Katsuyuki Shirai

Akiko Nakagawa

Takanori Abe

Masahiro Kawahara

Jun-ichi Saitoh

Tatsuya Ohno

Takashi Nakano

Use of FDG-PET in Radiation Treatment Planning for Thoracic Cancers

the aim studi explor estim renal function could explain variabl 123 imetaiodobenzylguanidin 123 imibg assess myocardi sympathet activ furthermor estim renal function were compar 123 imibg predictor cardiac death chronic heart failur chf semiquantit paramet 123 imibg myocardi uptak washout were calcul use earli heart mediastinum ratio late washout renal function calcul estim creatinin clearanc ecc estim glomerular filtrat rate egfr thirtynin patient chf 24 male age year nyha iii 17202 lvef were studi variabl ani semiquantit 123 imibg myocardi paramet could explain ecc egfr dure followup month were 6 cardiac death cox proport hazard regress analysi show late onli independ predictor cardiac death chisquar 32 regress coeffici 4095 standard error 2063 hazard ratio 017 95 00000950 addition estim renal function did signific chang chisquar model semiquantit 123 imibg myocardi paramet independ estim renal function addit cardiac sympathet innerv assess 123 imibg scintigraphi seem superior renal function predict cardiac death chf patient

Derk O. Verschure

G. Aernout Somsen

Berthe L. F. van Eck-Smit

Hein J. Verberne

Renal Function in Relation to Cardiac <sup>123</sup>I-MIBG Scintigraphy in Patients with Chronic Heart Failure

objectiv determin preval incidentaloma patient popul known thyroid malign who underw whole bodi fdgpet stage restag neoplasia the addit aim studi evalu feasibl use petct screen tool malign thyroid incidentaloma method retrospect review medic record all thyroid exam done our institut between januari 1 2000 august 20 2008 made criterion pet primari method detect incidentaloma result from total 8464 thyroid exam 156 incidentaloma were found 40 incidentaloma underw anatomopatholog analysi which use gold standard chisquar analysi use analyz data there signific associ between suv valu preval incidentaloma discuss from januari 1 2000 august 20 2008 incidentaloma have preval 184 our institut 38 incidentaloma were biopsi were character repres malign tumor conclus focal abnorm fdg uptak repres incidentaloma must follow biopsi impract use pet screen tool detect incidentaloma general popul must done patient histori ani type cancer

Miguel Hernandez Pampaloni

Aung Z. Win

Prevalence and Characteristics of Incidentalomas Discovered by Whole Body FDG PETCT

hepatocellular carcinoma hcc 5th most common tumour worldwid has dark prognosi for nonoper case metabol radiotherapi lipiodol label emitt promis therapeut option the comprehens cancer centr eugèn marqui nation graduat school chemistri renn enscr have joint develop stabl effici label lipiodol rhenium188 mev treatment hcc the major mileston develop from first synthes recent first inject man describ

Nicolas Lepareur

Valérie Ardisson

Nicolas Noiret

Etienne Garin

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</svg>-SSS/Lipiodol: Development of a Potential Treatment for HCC from Bench to Bedside

breastconserv surgeri involv complet excis tumour while limit amount normal tissu remov which technic challeng achiev especi given limit intraop guidanc avail surgeon this studi evalu feasibl radioimmunoguid surgeri rigs guid detect delin tumour intraop the pointrespons function commerci gammaraydetect probe gdp determin function radionuclid 131 111 99m energywindow threshold collim length 0030cm this function use calcul minimum detect tumour volum mdtvs minimum tumourtobackground activ concentr ratio effect delin breast tumour model the gdp had larger mdtvs higher minimum requir tumour delin 131 than 111 99m shown 111 benefit use collim length 05cm for model use minimum requir requir effect tumour delin 5 2 0 4 rigs has potenti signific improv accuraci breastconserv surgeri howev befor benefit can realiz novel radiopharmaceut need develop have higher specif cancer tissu vivo than what current avail

Ananth Ravi

Raymond M. Reilly

Claire M. B. Holloway

Curtis B. Caldwell

Feasibility Evaluation of Radioimmunoguided Surgery of Breast Cancer

the aim studi investig whether 111 indiumlabel recombin fviia rfviia could potenti radiopharmaceut local bleed sourc dtpaconjug rfviia radiolabel 111 chlorid vitro bind effici 111 indtparfviia f1a2mabsepharos 99 buffer while 8882 serum the bind effici 111 indtparfviia 1209 sepharos 48 buffer wherea 3936 serum respect vivo experi conduct healthi rat gamma camera imag were taken immedi after administr 1618 mbq 111 indtparfviia 120130 min five min after administr 111 indtparfviia percentag 111 activ 60 cardiac region 245 liver region after 2 hour activ decreas 33 heart while had increas 420 liver the 111 indtparfviia might potenti radiopharmaceut visualis tissu signific express acut bleed lesion gastrointestin tract

Amarnadh Nalla

Inge Buch

Maibritt Sigvardt

Rasmus Poul Bodholdt

Andreas Kjaer

Birger Hesse

<sup><b>111</b></sup>Indium Labelling of Recombinant Activated Coagulation Factor VII: In Vitro and Preliminary In Vivo Studies in Healthy Rats

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International Journal of Molecular Imaging

International Journal of Molecular Imaging