Research Article

Lactobacillus rhamnosus GG Suppresses Meningitic E. coli K1 Penetration across Human Intestinal Epithelial Cells In Vitro and Protects Neonatal Rats against Experimental Hematogenous Meningitis

Table 1

The rates of E. coli colonization, bacteremia, and meningitis in rat pups after receiving E44 or E44 plus LGG.

TreatmentNo. of animalNo. of pups with positive LGG culture in bloodNo. (%) of pups with intestinal colonization (E44)No. (%) of pups with bacteremia (105 to 108 CFU/mL) (E44)No. (%) of pups with meningitisa

E441414 (100)9 (64)3 (21)
E44 + LGG1408 (57)0 (0)0 (0)

aDefined as positive culture of CSF.