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International Journal of Microbiology
Volume 2010, Article ID 187373, 21 pages
http://dx.doi.org/10.1155/2010/187373
Research Article

Functional Promiscuity of Homologues of the Bacterial ArsA ATPases

Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA

Received 3 July 2010; Accepted 7 September 2010

Academic Editor: Ingolf Figved Nes

Copyright © 2010 Rostislav Castillo and Milton H. Saier. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1: Dendogram of the phylogenetic tree shown in Fig. 1. Proteins are arranged according to cluster and order within the cluster as seen in Fig. 1.

Figure S2: Phylogenetic trees showing the coevolution of (A) ArsA and (B) ArsB homologues, (C) ArsA and (D) Acr3 homologues, and (E) ArsA and (F) ArsP homologues, encoded within the same genomes. For these trees, we use the following system of nomenclature to better designate the added protein pairs not found within the same operons. The first digit indicates separate organisms with the same three letter code (ex: Aaa1, Aaa2), the second digit indicates paralogues, if present (ex: Aaa1-1, Aaa1-2). If the transporter is located within the same genome, but not the same operon as thearsA, the letter E, standing for elsewhere, follows the name (ex: Aaa1-3E).

Figure S3: Phylogenetic trees showing the coevolution of (A) ArsA and (B) ArsD homologues encoded within the same operon. The methodology was as described in Fig. 1.

  1. Supplementary Material