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International Journal of Microbiology
Volume 2010, Article ID 191585, 10 pages
Research Article

Skew-Laplace and Cell-Size Distribution in Microbial Axenic Cultures: Statistical Assessment and Biological Interpretation

1Departament de Probabilitat, Lògica i Estadística, Facultat de Matemàtiques, Universitat de Barcelona, Gran Via, 585, 08007-Barcelona, Spain
2Departament de Microbiologia, Universitat de Barcelona, Av. Diagonal, 645, 08028 Barcelona, Spain
3Tres Cantos Medicines Development Campus, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Spain
4Department of Chemistry & Chemical Biology, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, NJ 07030, USA

Received 27 May 2009; Revised 27 October 2009; Accepted 15 March 2010

Academic Editor: Marcel H. Zwietering

Copyright © 2010 Olga Julià et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report a skew-Laplace statistical analysis of both flow cytometry scatters and cell size from microbial strains primarily grown in batch cultures, others in chemostat cultures and bacterial aquatic populations. Cytometry scatters best fit the skew-Laplace distribution while cell size as assessed by an electronic particle analyzer exhibited a moderate fitting. Unlike the cultures, the aquatic bacterial communities clearly do not fit to a skew-Laplace distribution. Due to its versatile nature, the skew-Laplace distribution approach offers an easy, efficient, and powerful tool for distribution of frequency analysis in tandem with the flow cytometric cell sorting.