Aerosol Infection Model of Tuberculosis in Wistar Rats

<table>Course of infection of <i>M. tuberculosis</i> H37Rv in Rat lungs following low-grade aerosol infection.  (<span style="font-family:monospace">▴</span>): Course of infection and CFU obtained during weeks 1–7 in study 1.  (■): Course of infection and CFU obtained over weeks 2–18 in study 2.  Drug treatment started at week 4 postinfection.  Inset shows a rat lung at thirteen-week post infection with multiple macroscopic nodular granulomas all the lung lobes following aerosol infection with <i>M. tuberculosis. </i></table>

International Journal of Microbiology

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Figure 2: Aerosol Infection Model of Tuberculosis in Wistar Rats 