Candida albicans versus Candida dubliniensis: Why Is C. albicans More Pathogenic?

Table 1

Comparison of C. albicans and C. dubliniensis.

	C. albicans	C. dubliniensis	References
Growth and morphology
Growth at ≥42°C	Yes	No	[39, 41]
Growth in high salt media	Yes	No	[39, 40]
Hypha formation in YPD + serum	Yes	Poor	[16, 42]
Hypha formation in water + serum	Yes	Yes	[42]
RHE infection model	yeasts and hyphae	yeasts only	[17]
Genome
Chromosome number	8	9–11 chromosome-sized fragments	[7]
No. of species-specific genes	168	29	[32]
ALS3	Present	Absent	[32]
HYR1	Present	Absent	[32]
SAP4, 5 and 6	All three genes	One gene	[32]
HWP1	Present	Divergent	[32]
TLO family	14 genes	2 genes	[32]