LiF Reduces MICs of Antibiotics against Clinical Isolates of Gram-Positive and Gram-Negative Bacteria

Table 1

MICs (μg/mL) of doxycycline, ceftazidime, and sulfamethoxazole-trimethoprim alone or in combination with LiF on Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.

	Antimicrobial agents
MIC (μg/mL)	DOX	DOX + LiF	CFT	CFT + LiF	TMX	TMX + LiF
Bacterial strain
E. faecalis ATCC 29212	8.0	4.0	NT	NT	0.125	0.06
S. aureus ATCC 29213	0.125	0.03	2.0	1.0	0.50	0.25
E. coli ATCC 25922	1.0	0.5	0.25	0.06	0.25	0.06
P. aeruginosa ATCC 27653	NT	NT	2.0	1.0	16.0	8.0

DOX: doxycycline, CFT: ceftazidime, TMX: sulfamethoxazole-trimethoprim, NT: not tested.