Application of Bioluminescence Imaging for In Vivo Monitoring of Fungal Infections

Figure 1

Bioluminescence imaging of invasive aspergillosis. The depicted mouse was immunosuppressed with cortisone acetate and infected intranasally with the bioluminescent A. fumigatus strain C3. Bioluminescence was acquired 28 h after infection. Light emission is detected from both lung lobes indicating the establishment of bronchopulmonary aspergillosis. (Figure kindly provided by O. Ibrahim-Granet).