TY - JOUR
A2 - Wang, Jian-Wei
AU - Imade, Paul Erhunmwunse
AU - Eghafona, Nosakhare Odeh
PY - 2015
DA - 2015/04/30
TI - Viral Agents of Diarrhea in Young Children in Two Primary Health Centers in Edo State, Nigeria
SP - 685821
VL - 2015
AB - Enteric viruses have been shown to be responsible for diarrhea among children during their early childhood. This study was carried out to determine the prevalence of rotavirus, adenovirus, and norovirus infection in young children with diarrhea in two primary health centers in Edo State, Nigeria. A total of 223 stool specimens were collected from children aged 0–36 months with clinical signs of diarrhea and 59 apparently healthy age-matched children as control. These specimens were investigated for three viral agents using immunochromatographic technique (ICT). The overall results showed that at least one viral agent was detected in 95/223 (42.6%) of the children with diarrhea while the control had none. The prevalence of rotavirus was 28.3%, adenovirus 19.3%, and norovirus 3.6%. There was a significant association between age group and infection (P<0.0001). Seasonal pattern of enteric viruses was not statistically significant (P=0.17). The overall coinfection rate was 7.6% and rotavirus-adenovirus coinfection had the highest with 5.4%. Rotavirus was the most prevalent viral agent. Coinfections are not uncommon among the population studied. The most commonly associated clinical symptom of viral diarrhea in this study was vomiting. Viral diagnostic tests are advocated for primary health care facilities in this locality.
SN - 1687-918X
UR - https://doi.org/10.1155/2015/685821
DO - 10.1155/2015/685821
JF - International Journal of Microbiology
PB - Hindawi Publishing Corporation
KW -
ER -