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International Journal of Microbiology
Volume 2016, Article ID 8451728, 14 pages
http://dx.doi.org/10.1155/2016/8451728
Review Article

Bacteria in Cancer Therapy: Renaissance of an Old Concept

1Department of Molecular Immunology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany
2Institute of Immunology, Hannover Medical School, 30625 Hannover, Germany

Received 23 September 2015; Revised 3 February 2016; Accepted 11 February 2016

Academic Editor: Todd R. Callaway

Copyright © 2016 Sebastian Felgner et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [33 citations]

The following is the list of published articles that have cited the current article.

  • Sebastian Felgner, Dino Kocijancic, Vinay Pawar, and Siegfried Weiss, “Biomimetic Salmonella: A Next-Generation Therapeutic Vector?,” Trends in Microbiology, 2016. View at Publisher · View at Google Scholar
  • Amin Talebi Bezmin Abadi, “Comment on “Bacteria in Cancer Therapy: Renaissance of an Old Concept”,” International Journal of Microbiology, vol. 2016, pp. 1–1, 2016. View at Publisher · View at Google Scholar
  • Chuong Nguyen, and Van Duy Nguyen, “Discovery of Azurin-Like Anticancer Bacteriocins from Human Gut Microbiome through Homology Modeling and Molecular Docking against the Tumor Suppressor p53,” BioMed Research International, vol. 2016, pp. 1–12, 2016. View at Publisher · View at Google Scholar
  • Sebastian Felgner, Dino Kocijancic, Michael Frahm, Ulrike Heise, Manfred Rohde, Kurt Zimmermann, Christine Falk, Marc Erhardt, and Siegfried Weiss, “ Immunity during Salmonella -mediated tumor therapyEngineered Salmonella enterica serovar Typhimurium overcomes limitations of anti-bacterial immunity in bacteria-mediated tumor therapy ,” OncoImmunology, pp. 00–00, 2017. View at Publisher · View at Google Scholar
  • Gang Xin, David M Schauder, Ryan Zander, and Weiguo Cui, “Two is better than one: advances in pathogen-boosted immunotherapy and adoptive T-cell therapy,” Immunotherapy, vol. 9, no. 10, pp. 837–849, 2017. View at Publisher · View at Google Scholar
  • Sebastian Felgner, Vinay Pawar, Dino Kocijancic, Marc Erhardt, and Siegfried Weiss, “Tumour-targeting bacteria-based cancer therapies for increased specificity and improved outcome,” Microbial Biotechnology, 2017. View at Publisher · View at Google Scholar
  • Petra Kucerova, Jitka Vlasakova, and Monika Cervinkova, “Coley?s toxin and BCG vaccine in prevention and treatment of malignant melanoma in humans,” Reviews in Medical Microbiology, vol. 28, no. 3, pp. 124–128, 2017. View at Publisher · View at Google Scholar
  • Min Sun Kim, Seung Hyuk Choi, Jeong In Yang, and Ki Hong Kim, “Production of RNase III-knockout, auxotrophic Edwardsiella tarda mutant for delivery of long double-stranded RNA and evaluation of its immunostimulatory potential,” Fish & Shellfish Immunology, 2017. View at Publisher · View at Google Scholar
  • John P Hays, “Why is scientific research on 'data-poor' microorganisms being ignored?,” Future Microbiology, vol. 12, no. 8, pp. 645–650, 2017. View at Publisher · View at Google Scholar
  • Dino Kocijancic, Sara Leschner, Sebastian Felgner, Ronja-Melinda Komoll, Michael Frahm, Vinay Pawar, and Siegfried Weiss, “Therapeutic benefit of Salmonella attributed to LPS and TNF-α is exhaustible and dictated by tumor susceptibility.,” Oncotarget, vol. 8, no. 22, pp. 36492–36508, 2017. View at Publisher · View at Google Scholar
  • Regino Mercado-Lubo, and Beth A McCormick, “ Can a nanoparticle that mimics Salmonella effectively combat tumor chemotherapy resistance? ,” Nanomedicine, 2017. View at Publisher · View at Google Scholar
  • Mark Bazett, Amanda M. Costa, Momir Bosiljcic, Rebecca M. Anderson, Matthew P. Alexander, Stephanie WY Wong, Salim Dhanji, Jenny MH Chen, Jim Pankovich, Stephen Lam, Simon Sutcliffe, Hal Gunn, Shirin Kalyan, and David W. Mullins, “Harnessing innate lung anti-cancer effector functions with a novel bacterial-derived immunotherapy,” OncoImmunology, pp. 00–00, 2017. View at Publisher · View at Google Scholar
  • Jessica Pahle, and Wolfgang Walther, “Bacterial Toxins for Oncoleaking Suicidal Cancer Gene Therapy,” Current Strategies in Cancer Gene Therapy, vol. 209, pp. 95–110, 2017. View at Publisher · View at Google Scholar
  • Kati Turkowski, Javier Mora, Werner Seeger, Andreas Weigert, Rajkumar Savai, Xiang Zheng, and Bernhard Brüne, “Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy,” Oncotarget, vol. 8, no. 29, pp. 48436–48452, 2017. View at Publisher · View at Google Scholar
  • Dino Kocijancic, Sebastian Felgner, Michael Frahm, Kurt Zimmermann, Siegfried Weiss, Tim Schauer, Ulrike Heise, and Marc Erhardt, “Local application of bacteria improves safety of Salmonella-mediated tumor therapy and retains advantages of systemic infection,” Oncotarget, vol. 8, no. 30, pp. 49988–50001, 2017. View at Publisher · View at Google Scholar
  • Sabiha Imran, Twinkle Gupta, Aarti Arora, and Nilanjan Das, “A comparative study of antimicrobial profile having broad spectrum bacteriocins against antibiotics,” Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 9, pp. 44–47, 2017. View at Publisher · View at Google Scholar
  • Arthur Dyer, Richard Baugh, Suet Lin Chia, Sally Frost, Iris, Egon J. Jacobus, Hena Khalique, Tzveta D. Pokrovska, Eleanor M. Scott, William K. Taverner, Len W. Seymour, and Janet Lei, “Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference,” Cancer Gene Therapy, 2018. View at Publisher · View at Google Scholar
  • Neil S. Forbes, Robert S. Coffin, Liang Deng, Laura Evgin, Steve Fiering, Matthew Giacalone, Claudia Gravekamp, James L. Gulley, Hal Gunn, Robert M. Hoffman, Balveen Kaur, Ke Liu, Herbert Kim Lyerly, Ariel E. Marciscano, Eddie Moradian, Sheryl Ruppel, Daniel A. Saltzman, Peter J. Tattersall, Steve Thorne, Richard G. Vile, Halle Huihong Zhang, Shibin Zhou, and Grant McFadden, “White paper on microbial anti-cancer therapy and prevention,” Journal for ImmunoTherapy of Cancer, vol. 6, no. 1, 2018. View at Publisher · View at Google Scholar
  • Suneesh Kaimala, Ashraf Al-Sbiei, Otavio Cabral-Marques, Maria J. Fernandez-Cabezudo, and Basel K. Al-Ramadi, “Attenuated Bacteria as Immunotherapeutic Tools for Cancer Treatment,” Frontiers in Oncology, vol. 8, 2018. View at Publisher · View at Google Scholar
  • Jing Song, Yu Zhang, Chengqian Zhang, Xiaohui Du, Zhe Guo, Yanbin Kuang, Yingyan Wang, Peng Wu, Kun Zou, Lijuan Zou, Jianxin Lv, and Qi Wang, “A microfluidic device for studying chemotaxis mechanism of bacterial cancer targeting,” Scientific Reports, vol. 8, no. 1, 2018. View at Publisher · View at Google Scholar
  • Kouhsari, Ghadimi-Daresajini, Mousavi, Moghaderi, Yaseri, Amirmozafari, Mahdavi, Abbasian, and Abdollahi, “The potential roles of bacteria to improve radiation treatment outcome,” Clinical and Translational Oncology, vol. 20, no. 2, pp. 127–139, 2018. View at Publisher · View at Google Scholar
  • Yensi Flores Bueso, Panos Lehouritis, and Mark Tangney, “In situ biomolecule production by bacteria; a synthetic biology approach to medicine,” Journal of Controlled Release, 2018. View at Publisher · View at Google Scholar
  • Colleen S. Curran, Ben Prickril, Avraham Rasooly, Magdelena Thurin, Elad Sharon, and Min He, “Report on the NCI microbial-based cancer therapy conference,” Cancer Immunology Research, vol. 6, no. 2, pp. 122–126, 2018. View at Publisher · View at Google Scholar
  • Patricia Masso-Welch, Sofia Girald Berlingeri, Natalie King-Lyons, Lorrie Mandell, John Hu, Christopher Greene, Matthew Federowicz, Peter Cao, Terry Connell, and Yasser Heakal, “LT-IIc, A Bacterial Type II Heat-Labile Enterotoxin, Induces Specific Lethality in Triple Negative Breast Cancer Cells by Modulation of Autophagy and Induction of Apoptosis and Necroptosis,” International Journal of Molecular Sciences, vol. 20, no. 1, pp. 85, 2018. View at Publisher · View at Google Scholar
  • SeungBeum Suh, Ami Jo, Mahama A. Traore, Ying Zhan, Sheryl L. Coutermarsh-Ott, Veronica M. Ringel-Scaia, Irving C. Allen, Richey M. Davis, and Bahareh Behkam, “Nanoscale Bacteria-Enabled Autonomous Drug Delivery System (NanoBEADS) Enhances Intratumoral Transport of Nanomedicine,” Advanced Science, pp. 1801309, 2018. View at Publisher · View at Google Scholar
  • Amirhosein Kefayat, Fatemeh Ghahremani, Hasan Motaghi, Soodabeh Rostami, and Masoud A. Mehrgardi, “ Alive attenuated Salmonella as a cargo shuttle for smart carrying of gold nanoparticles to tumour hypoxic regions ,” Journal of Drug Targeting, pp. 1–10, 2018. View at Publisher · View at Google Scholar
  • Ibrahim Khalil, Martin Khechara, Sathishkumar Kurusamy, Angel Armesilla, Abhishek Gupta, Barbara Mendrek, Tamara Khalaf, Mariastella Scandola, Maria Focarete, Marek Kowalczuk, and Iza Radecka, “Poly-Gamma-Glutamic Acid (γ-PGA)-Based Encapsulation of Adenovirus to Evade Neutralizing Antibodies,” Molecules, vol. 23, no. 10, pp. 2565, 2018. View at Publisher · View at Google Scholar
  • Emile J. Clappaert, Aleksandar Murgaski, Helena Van Damme, Mate Kiss, and Damya Laoui, “Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy,” Frontiers in Immunology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Thais Bascuas, María Moreno, Sofía Grille, and José A. Chabalgoity, “Salmonella Immunotherapy Improves the Outcome of CHOP Chemotherapy in Non-Hodgkin Lymphoma-Bearing Mice,” Frontiers in Immunology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Klaudia Łukasiewicz, and Marek Fol, “Microorganisms in the Treatment of Cancer: Advantages and Limitations,” Journal of Immunology Research, vol. 2018, pp. 1–8, 2018. View at Publisher · View at Google Scholar
  • Gella Maelys Ngandeu Neubi, Yaw Opoku-Damoah, Xiaochen Gu, Yue Han, Jianping Zhou, and Yang Ding, “Bio-inspired drug delivery systems: an emerging platform for targeted cancer therapy,” Biomaterials Science, 2018. View at Publisher · View at Google Scholar
  • Thuy Phan, Vu H. Nguyen, Marcela S. D’Alincourt, Edwin R. Manuel, Teodora Kaltcheva, Weimin Tsai, Bruce R. Blazar, Don J. Diamond, and Laleh G. Melstrom, “Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth,” Cancer Gene Therapy, 2019. View at Publisher · View at Google Scholar
  • Silvia Vivarelli, Rossella Salemi, Saverio Candido, Luca Falzone, Maria Santagati, Stefania Stefani, Francesco Torino, Giuseppe Banna, Giuseppe Tonini, and Massimo Libra, “Gut Microbiota and Cancer: From Pathogenesis to Therapy,” Cancers, vol. 11, no. 1, pp. 38, 2019. View at Publisher · View at Google Scholar