Table of Contents Author Guidelines Submit a Manuscript
International Journal of Microbiology
Volume 2016, Article ID 8469018, 7 pages
http://dx.doi.org/10.1155/2016/8469018
Research Article

Oral Administration of Lactobacillus plantarum 299v Reduces Cortisol Levels in Human Saliva during Examination Induced Stress: A Randomized, Double-Blind Controlled Trial

1Food Hygiene, Department of Food Technology, Engineering and Nutrition, Lund University, P.O. Box 124, 22100 Lund, Sweden
2Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden
3Probi AB, Ideon Gamma 1, 223 70 Lund, Sweden

Received 27 July 2016; Revised 21 October 2016; Accepted 1 November 2016

Academic Editor: Giuseppe Comi

Copyright © 2016 Hannah Andersson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Ait-Belgnaoui, H. Durand, C. Cartier et al., “Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats,” Psychoneuroendocrinology, vol. 37, no. 11, pp. 1885–1895, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. S. R. Knowles, E. A. Nelson, and E. A. Palombo, “Investigating the role of perceived stress on bacterial flora activity and salivary cortisol secretion: a possible mechanism underlying susceptibility to illness,” Biological Psychology, vol. 77, no. 2, pp. 132–137, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Fan, Y. Tang, Q. Lu et al., “Dynamic changes in salivary cortisol and secretory immunoglobulin A response to acute stress,” Stress and Health, vol. 25, no. 2, pp. 189–194, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Tsujita and K. Morimoto, “Secretory IgA in saliva can be a useful stress marker,” Environmental Health and Preventive Medicine, vol. 4, no. 1, pp. 1–8, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. L. M. Tomfohr, K. M. Edwards, and J. E. Dimsdale, “Is obstructive sleep apnea associated with cortisol levels? A systematic review of the research evidence,” Sleep Medicine Reviews, vol. 16, no. 3, pp. 243–249, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. P. Brandtzaeg, “Do salivary antibodies reliably reflect both mucosal and systemic immunity?” Annals of the New York Academy of Sciences, vol. 1098, pp. 288–311, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. J. M. Crawford, M. A. Taubman, and D. J. Smith, “Minor salivary glands as a major source of secretory immunoglobulin A in the human oral cavity,” Science, vol. 190, no. 4220, pp. 1206–1209, 1975. View at Publisher · View at Google Scholar · View at Scopus
  8. FAO/WHO, Joint FAO/WHO Working Group Report on Drafting Guidelines for the Evaluation of Probiotics in Food, April and May 2002.
  9. K. Niedzielin, H. Kordecki, and B. Birkenfeld, “A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome,” European Journal of Gastroenterology and Hepatology, vol. 13, no. 10, pp. 1143–1147, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Nobaek, M.-L. Johansson, G. Molin, S. Ahrné, and B. Jeppsson, “Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome,” The American Journal of Gastroenterology, vol. 95, no. 5, pp. 1231–1238, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Ahrné and M.-L. J. Hagslätt, “Effect of lactobacilli on paracellular permeability in the gut,” Nutrients, vol. 3, no. 1, pp. 104–117, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. M. G. Gareau, J. Jury, and G. MacQueen, “Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation,” Gut, vol. 56, no. 11, pp. 1522–1528, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. P. Cáceres, S. Montes, N. Vega, S. Cruchet, O. Brunser, and M. Gotteland, “Effects of Lactobacillus rhamnosus HN001 on acute respiratory infections and intestinal secretory IgA in children,” Journal of Pediatric Infectious Diseases, vol. 5, no. 4, pp. 353–362, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Viljanen, M. Kuitunen, T. Haahtela, K. Juntunen-Backman, R. Korpela, and E. Savilahti, “Probiotic effects on faecal inflammatory markers and on faecal IgA in food allergic atopic eczema/dermatitis syndrome infants,” Pediatric Allergy and Immunology, vol. 16, no. 1, pp. 65–71, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Cohen, D. Janicki-Deverts, W. J. Doyle et al., “Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk,” Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 16, pp. 5995–5999, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. R. M. Sapolsky, L. M. Romero, and A. U. Munck, “How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions,” Endocrine Reviews, vol. 21, no. 1, pp. 55–89, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Levenstein, C. Prantera, V. Varvo et al., “Development of the perceived stress questionnaire: a new tool for psychosomatic research,” Journal of Psychosomatic Research, vol. 37, no. 1, pp. 19–32, 1993. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Eliasson, D. Birkhed, G. Heyden, and N. Strömberg, “Studies on human minor salivary gland secretions using the Periotron® method,” Archives of Oral Biology, vol. 41, no. 12, pp. 1179–1182, 1996. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Sonesson, K. Hamberg, M.-L. L. Wallengren, L. Matsson, and D. Ericson, “Salivary IgA in minor-gland saliva of children, adolescents, and young adults,” European Journal of Oral Sciences, vol. 119, no. 1, pp. 15–20, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. Labmedicin Skåne, Klinisk Kemi, Saliv-Kortisol på Cobas (NPU01788), November 2011.
  21. E. Filaire, J. Bonis, and G. Lac, “Relationships between physiological and psychological stress and salivary immunoglobulin A among young female gymnasts,” Perceptual and Motor Skills, vol. 99, no. 2, pp. 605–617, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. K. Krzywkowski, E. W. Petersen, K. Ostrowski et al., “Effect of glutamine and protein supplementation on exercise-induced decreases in salivary IgA,” Journal of Applied Physiology, vol. 91, no. 2, pp. 832–838, 2001. View at Google Scholar · View at Scopus
  23. M. Quednau, S. Ahrné, A. C. Petersson, and G. Molin, “Identification of clinically important species of Enterococcus within 1 day with randomly amplified polymorphic DNA (RAPD),” Current Microbiology, vol. 36, no. 6, pp. 332–336, 1998. View at Publisher · View at Google Scholar · View at Scopus
  24. C. Fujimaru, H. Okamura, M. Kawasaki, T. Kakuma, C. Yoshii, and T. Matsuishi, “Self-perceived work-related stress and its relation to salivary IgA, cortisol and 3-methoxy-4-hydroxyphenyl glycol levels among neonatal intensive care nurses,” Stress and Health, vol. 28, no. 2, pp. 171–174, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. J. A. Bosch, C. Ring, E. J. C. de Geus, E. C. I. Veerman, and A. V. N. Amerongen, “Stress and secretory immunity,” International Review of Neurobiology, vol. 52, pp. 213–253, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. E. Tiollier, M. Chennaoui, D. Gomez-Merino, C. Drogou, E. Filaire, and C. Y. Guezennec, “Effect of a probiotics supplementation on respiratory infections and immune and hormonal parameters during intense military training,” Military Medicine, vol. 172, no. 9, pp. 1006–1011, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Campisi, Y. Bravo, J. Cole, and K. Gobeil, “Acute psychosocial stress differentially influences salivary endocrine and immune measures in undergraduate students,” Physiology and Behavior, vol. 107, no. 3, pp. 317–321, 2012. View at Publisher · View at Google Scholar · View at Scopus