Research Article

Antimicrobial Activity of a Cationic Guanidine Compound against Two Pathogenic Oral Bacteria

Table 1

Comparative table of the physicochemical and biological properties of CatDex and CHX.

CharacteristicsCHXCatDex

Gold standard antiseptic?

SolubilityHydrophilicHydrophilic

ChargeCationic polybiguanide (polybiguanide)Cationic

Molecular weight1340 g moL−155 KD

Density1.01 g cc−1?

pH5.5–7.56.5

AppearanceBlue translucent liquidAmber translucent liquid

ActivityBactericide 
Fungicide 
Antiviral
Antitumour efficacy [15, 16]

Interaction with cellsElectrostatic interaction with cationic lipopolysaccharides and teichoic acid of cell wall [19]Electrostatic interaction with anionic structures of cytoplasm [15, 17]