Research Article
Enterococcus faecium TIR-Domain Genes Are Part of a Gene Cluster Which Promotes Bacterial Survival in Blood
Table 1
ORFs in the putative MGE-TirE of E. faecium strain E1162.
| Locus tag in E1162 | Product NCBI | CDD (Conserved Domain Database) | Phyre2 prediction (putative function) | SignalP prediction (secretion signal) | Size (Da) | Name |
| EFME1162_RS19580 | Site-specific integrase | DNA-binding integrase | Integrase | — | 44551 | int1 | EFME1162_RS19585 | — | TIR-like | TIR domain | — | 18496 | tirE1 | EFME1162_RS19590 | — | Sir2-like | Nucleotide binding | — | 55003 | hp1 | EFME1162_RS19595 | — | TIR-like | TIR domain | — | 32901 | tirE2 | EFME1162_RS19600 | Transcription regulator | DNA binding | DNA binding | — | 9466 | hp2 | EFME1162_RS19605 | — | — | — | Yes | 29307 | hp3 | EFME1162_RS0109495 | — | — | — | — | 12407 | hp4 | EFME1162_RS19610 | — | — | — | — | 8588 | hp5 | EFME1162_RS19615 | — | DnaJ super family | Transcription regulator | Yes | 98796 | hp6 | EFME1162_RS0109500 | — | — | — | — | 8445 | hp7 | EFME1162_RS19620 | — | — | DNA binding | — | 34840 | hp8 | EFME1162_RS19625 | DNA binding protein | DNA binding | DNA binding | — | 11591 | hp9 | EFME1162_RS19630 | Transcription regulator | Transcription regulator | Transcription regulator | — | 31516 | hp10 | EFME1162_RS19635 | Site-specific integrase | Integrase | Integrase | — | 44970 | int2 |
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