Current Progress in the Structural and Biochemical Characterization of Proteins Involved in the Assembly of Lipopolysaccharide

Figure 14

MsbA. (a) Cytoplasmic-open conformation of MsbA bound to LPS (PDB: 5TV4) [104]. (b) Hydrophobicity surface of MsbA in (a). Orange is the hydrophobic end of the scale, and blue is the hydrophilic end. The mostly orange region roughly indicates the coverage of the nanodisc membrane in the electron density [104]. (c) Periplasmic-open conformation of MsbA bound to AMP-PNP ATP analogue (PDB: 3B60) [103].