Research Article
Screening and Antifungal Activity of a β-Carboline Derivative against Cryptococcus neoformans and C. gattii
Table 2
MIC of carbazole and β-carboline derivatives against Cryptococcus gattii and C. neoformans strains.
| | Substances | C. gattii VGII WM178/08 MIC (μg/mL) | C. neoformans VNI WM148/08 MIC (μg/mL) |
| | 8-Nitroharmane | 40 | 40 | | 9H-carbazole | 160 | 160 | | Harmane | 160 | 160 | | 8-Nitroharmine | 160 | 160 | | N-Acetyl-9H-carbazole | >320 | >320 | | Harmaline | >320 | >320 | | Harmalol | >320 | >320 | | Harmine | >320 | >320 | | Harmol | >320 | >320 | | 6-Nitroharmane | >320 | >320 | | 6-Nitroharmine | >320 | >320 | | Amphotericin B | 0.250 | 0.065 |
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