Research Article

Screening and Antifungal Activity of a β-Carboline Derivative against Cryptococcus neoformans and C. gattii

Table 5

Effect of exogenous ergosterol (400–1600 μg/mL) on the MIC of 8-nitroharmane against Cryptococcus neoformans and Candida albicans.

SubstancesC. neoformans VNI WM148/08 MIC (µg/mL)C. albicans ATCC 36232 MIC (µg/mL)
ControlErgosterol (µg/mL)ControlErgosterol (µg/mL)
0400800160004008001600

8-Nitroharmane40404040160160160160
Amphotericin B0.0650.0650.2500.5000.50.51.02.0