Research Article
Screening and Antifungal Activity of a β-Carboline Derivative against Cryptococcus neoformans and C. gattii
Table 5
Effect of exogenous ergosterol (400–1600 μg/mL) on the MIC of 8-nitroharmane against Cryptococcus neoformans and Candida albicans.
| Substances | C. neoformans VNI WM148/08 MIC (µg/mL) | C. albicans ATCC 36232 MIC (µg/mL) | Control | Ergosterol (µg/mL) | Control | Ergosterol (µg/mL) | 0 | 400 | 800 | 1600 | 0 | 400 | 800 | 1600 |
| 8-Nitroharmane | 40 | 40 | 40 | 40 | 160 | 160 | 160 | 160 | Amphotericin B | 0.065 | 0.065 | 0.250 | 0.500 | 0.5 | 0.5 | 1.0 | 2.0 |
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