Screening and Antifungal Activity of a β-Carboline Derivative against Cryptococcus neoformans and C. gattii

Table 6

Percent leakage of substances absorbing at 260 nm from Cryptococcus neoformans and Candida albicans induced by 8-nitroharmane.

Percent (%) leakage of substances absorbing at 260 nm
Substances (concentration)	C. neoformans VNI WM148/08				Substances (concentration)	C. albicans ATCC 36232
	1 h	2 h	4 h	6 h		1 h	2 h	4 h	6 h
8-Nitroharmane (40 µg/mL)	0	10	30	60	8-Nitroharmane (160 µg/mL)	0	10	30	60
8-Nitroharmane (320 µg/mL)	10	40	50	60	8-Nitroharmane (640 µg/mL)	10	40	50	60
HClO4 (1.2 M)	100	100	100	100	HClO4 (1.2 M)	10	100	100	100
Control (blank)	0	0	0	0	Control (blank)	0	0	0	0