In Vitro Modulator Effect of Total Extract from the Endophytic Paenibacillus polymyxa RNC-D in Leishmania (Leishmania) amazonensis and Macrophages

Table 5

NO concentration in the cells treated and not treated with Paenibacillus polymyxa RNC-D extract after infection with Leishmania amazonensis.

Group	24 h (µM)	48 h (µM)
Control	4.094 ± 0.684^NS	2.907 ± 0.138^NS
0.1 mg/mL	4.353 ± 0.159^NS	3.438 ± 0.665^NS
0.5 mg/mL	4.268 ± 0.104^NS	4.394 ± 0.481^NS
1 mg/mL	4.616 ± 0.352^NS	3.253 ± 0.542^NS
Amphotericin B 0.1 mM	3.585 ± 0.511^NS	3.137 ± 0.436^NS

The symbols and represent the significant difference between the treated group and the negative control group (only infected). NS: no statistical difference.