Research Article

Mathematical Model for Hepatocytic-Erythrocytic Dynamics of Malaria

Table 2

Symbols and description of parameters used in the model.

Parameter Description

The total rate of injection of sporozoites into liver due to mosquito bites
The death rate of sporozoites
Recruitment rate of susceptible hepatocytes from the bone marrow
Natural death rate of susceptible hepatocytes
The invasion rate of hepatocytes by sporozoites
Death rate of infected hepatocytes
Recruitment rate of susceptible RBCs by the bone marrow
The natural death rate of RBCs
The invasion rate of RBCs by merozoites
Death rates of IRBCs
The death rate of merozoites
Recruitment rate of macrophages from the bone marrow
The death rate of a macrophage
Elimination rate of IRBCs by macrophages
Production rate of hepatocytes due to presence of infected hepatocytes
Production rate of RBCs due to presence of IRBCs
Immunogenicity of IRBCs
Number of at which the recruitment of is a half of the maximum rate
Number of at which the recruitment of is a half of the maximum rate
Number of at which the recruitment of is a half of the maximum rate
The proportion of the merozoites that cause secondary infections
The average number of merozoites released per bursting IRBCs
The average number of merozoites released per bursting infected hepatocytes