Evaluation of Chitosan Based Polymeric Matrices for Sustained Stomach Specific Delivery of Propranolol Hydrochloride

Table 4

Drug release kinetics of HBS formulations of PHCL.

Formulation code	Zero order	First order	Higuchi	Korsmeyer-Peppas	value
J1	0.6399	0.9620	0.8814	—	0.54
J2	0.9471	0.9193	0.9945	0.8782	0.41
J3	0.9682	0.9851	0.9772	0.8614	0.51
J4	0.9314	0.7755	0.9975	0.8742	0.41
J5	0.9234	0.8674	0.9844	0.8072	0.43
J6	0.8577	0.8106	0.9728	0.8772	0.41
J7	0.9253	0.9258	0.9655	0.7018	0.24
J8	0.8685	0.9888	09881	—	1.28
J9	0.9948	0.9668	0.8933	0.8753	0.52

Determined for amount of drug released during the first h at 15 min interval.