Clinical Study

Effects of Moderate-to-Severe Impairment of the Estimated Glomerular Filtration Rate and of Proteinuria on the Central Hemodynamics and Arterial Stiffness in Middle-Aged Healthy Japanese Men

Table 1

Clinical characteristics of the entire study population.

Parameter

number2244
Age (y)
Height (cm)
BMI
WC (cm)
Smoking (%)707 (32)
ALC (N/LM/H) (%)291/1386/567 (13/62/25)
SBP (mmHg)
DBP (mmHg)
Pulse rate (bpm)
baPWV (m/s)
radial AI (%)
SBP 2 (mmHg)
TC (mmol/L)
HDL (mmol/L )
TG (mmol/L)
FPG (mmol/Ll)
eGFR (mL/min per 1.73 m2)
eGFR < 60 mL/min per 1.73 m2 (%)48 (2.1)
Proteinuria (%)65 (2.9)

Abbreviations. BMI: body mass index; WC: waist circumference; smoking: number of subjects who were smoking; ALC: (N: nondrinker, LM: light-to-moderate drinker (ethanol intake: 1–29 g/day), and H: heavy drinker (ethanol intake: ≥30 g/day)); SBP: systolic blood pressure; DBP: diastolic blood pressure; baPWV: brachial-ankle pulse wave velocity; radial AI: radial augmentation index; SBP2: second peak of the radial pressure waveform; TC: serum total cholesterol; HDL: serum high-density lipoprotein cholesterol; TG: serum triglycerides; FPG: fasting plasma glucose; eGFR: estimated glomerular filtration rate; eGFR < 60 mL/min per 1.73 m2: number of subjects with eGFR < 60 mL/min per 1.73 m2; proteinuria: number of subjects with proteinuria.