ADPKD: Prototype of Cardiorenal Syndrome Type 4

Table 1

Classification of cardiorenal syndorme (CRS).

Acute cardiorenal syndrome	CRS type 1	Abrupt worsening of cardiac function leading to acute kidney injury (AKI)
Chronic cardiorenal syndrome	CRS type 2	Chronic abnormalities in cardiac function causing progressive chronic kidney disease (CKD)
Acute renocardiac syndrome	CRS type 3	Sudden worsening of renal function causing acute cardiac dysfunction
Chronic renocardiac syndrome	CRS type 4	Condition of primary CKD leading to an impairment of the cardiac function (ventricular hypertrophy, diastolic dysfunction) and/or increased risk of adverse cardiovascular events.
Secondary cardiorenal syndrome	CRS type 5	Systemic disorders (e.g., sepsis) causing both cardiac and renal dysfunction