Table 1: Classification of cardiorenal syndorme (CRS).

Acute cardiorenal syndromeCRS type 1Abrupt worsening of cardiac function leading to acute kidney injury (AKI)

Chronic cardiorenal syndromeCRS type 2Chronic abnormalities in cardiac function causing progressive chronic kidney disease (CKD)
Acute renocardiac syndromeCRS type 3Sudden worsening of renal function causing acute cardiac dysfunction
Chronic renocardiac syndromeCRS type 4Condition of primary CKD leading to an impairment of the cardiac function (ventricular hypertrophy, diastolic dysfunction) and/or increased risk of adverse cardiovascular events.
Secondary cardiorenal syndromeCRS type 5Systemic disorders (e.g., sepsis) causing both cardiac and renal dysfunction