Acute Renal Failure, Microangiopathic Haemolytic Anemia, and Secondary Oxalosis in a Young Female Patient
Table 1
Biochemical and hematological parameters during admission.
Day of in hospital stay
Creatinine 55–100 μmol/L
Hb 11.5–16.5 g/dL
LDH (U/L) (220–450)
Platelets × 10−9/L (150–450)
Blood film
Plasma exchange (PE) or hemodialysis (HD)
1
1815
6.3
2205
84
HD (1)
2
1124
9.0
2039
127
PE (1)
2
881
8.8
726
112
HD (2)
3
615
8.7
615
140
PE (2) HD (3)
4
617
7.8
Poikilocytes, polychromasia, acanthocytes
PE (3)
7
730
8.8
639
241
Acanthocytes, polychromasia, helmet cells, red cell fragments (8% of RBC)
HD (4)
7
302
8.8
611
261
PE (4)
8
340
10
573
261
Occasional schistocyte
Biopsy
9
308
9.0
613
230
Approximately 6–8 fragmented cells per high-power field seen
PE (5)
10
255
10.2
694
296
3-4 fragments per high-power field
18
124
10.0
488
261
No fragmented cells
The resolution of creatinine, hemoglobin, lactate dehydrogenase, thrombocytopenia and fragmented cells on blood film, with plasma exchange and hemodialysis courses over a period of 18 days of in hospital stay. HD: hemodialysis, PE: plasma exchange.