Review Article

Hyponatremia and Congestive Heart Failure: A Marker of Increased Mortality and a Target for Therapy

Table 1

The actions of vasopressin and its receptors.

ReceptorLocationAction

V1aVascular smooth muscleVasoconstriction
Myocardial hypertrophy
PlateletsAggregation
MyometriumUterine contraction

V1bAnterior pituitaryAdrenocorticotropin hormone release

V2Renal collecting tubuleInduction of aquaporin-2
Free water absorption
Vascular endotheliumRelease of von Willebrand factor
Release of factor VIII