Table 2: Suggestions for organ transplantation strategies in PH1 patients according to residual GFR (ml/min per 1.73 m²), systemic involvement, and local facilities (from [68]).

Tx strategyCombined simultaneous liver + kidneyLiver first Kidney as a second stepIsolated kidneyIsolated liver

HD strategyPeroperative ± postoperative according to Pox and GFRStandard HD following liver Tx aiming at Pox <20 μmol/LPre- and peroperativeSometimes peroperative
NoNoNoOptional
YesNo(1) In developing countries
(2) In very selected patients
No
YesYesNoNo
Infantile form
(ESRD <2 years)
YesYes (emergency)NoNo

Abbreviations: ESRD end-stage renal disease; GFR glomerular filtration rate; HD hemodialysis; Pox plasma oxalate; Tx transplantation.