Relationship between Plasma Leptin Level and Chronic Kidney Disease

Table 2

Association between plasma leptin level and prevalence of chronic kidney disease (CKD).

Plasma leptin level	𝑁	CKD weighted %	Age, sex-adjusted odds ratio (95% confidence interval)	Multivariable-adjusted odds ratio (95% confidence interval)*
Quartile 1 (≤4.3 Fg/L)	1453	1.8	1 (referent)	1 (referent)
Quartile 2 (4.4–8.7 Fg/L)	1541	3.2	1.42(0.80to2.52)	1.35(0.73to2.52)
Quartile 3 (8.8–16.9 Fg/L)	1464	3.5	1.40(0.74to2.62)	1.34(0.63to2.87)
Quartile 4 (>16.9 Fg/L)	1452	6.3	3.25(1.61to6.55)	3.31(1.41to7.78)
P-trend			0.0019	0.0135
Log-transformed leptin	5820	3.6	1.57(1.23to2.01)	1.74(1.27to2.38)

∗Adjusted for age (years), sex (men, women), race-ethnicity (non-Hispanic whites, non-Hispanic blacks, Mexican Americans, others), education categories (<high school, high school, >high school), smoking (never, former, current), alcohol intake (never, former, current), body mass index (normal, overweight, obese), diabetes (absent, present), hypertension (absent, present), and serum total cholesterol (mg/dL).