Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model
Figure 1
The serum difference levels (one week after CP administration − before CP administration; Δ) of BUN, Cr, Mg, SOD, estradiol, and nitrite; the kidney and the uterus weights; the KTDS in vehicle, estradiol, or CP (the positive control group) alone-treated ovariectomized groups. The star indicates significant difference () when compared with the positive control groups. CP, ES, and PL on the horizontal axes stand for groups treated with CP (group 5), estradiol valerate (group 6), and vehicle (placebo, group 7), respectively.
