Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model

<table>Images (magnification ×100) of kidney tissue. PL, ES, CP, CPE, CPEVE, CPEVC, and CPEL inside the images stand for groups treated with vehicle (placebo, group 7), estradiol valerate (group 6), CP alone (group 5), estradiol and CP (group 1), estradiol plus vitamin E and CP (group 2), estradiol plus vitamin C and CP (group 3), and estradiol plus losartan and CP (group 4), respectively. No tissue damages were seen in PL and ES, but higher and almost similar tissue damages were observed in other groups.</table>

International Journal of Nephrology

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Figure 3: Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model 

Figure 3 | Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model 