Serum Galactose-Deficient IgA1 Level Is Not Associated with Proteinuria in Children with IgA Nephropathy
Table 2
Clinical and demographic features of individual subjects (prevalent cases).
Subject
Race/gender
Presentation
Age at biopsy
estGFR (mL/min/1.73 m2)
Urinary protein/ creatinine ratio
BMI percentile
SBP/DBP percentile
Serum Gd-IgA1 level (units/mL)
A2
AA/F
Gross hematuria,
15.9
98
1.13
99
95–99/95–99
1320
proteinuria
A3
C/F
Gross hematuria,
6.8
82
5.00
54
753
nephrotic syndrome
K1
C/M
Gross hematuria
11.2
87
1.40
99
50–90/50–90
704
K2
C/M
Microhematuria,
13.2
138
0.41
99
>99/50–90
919
proteinuria
M1
AA/M
Microhematuria,
9.3
108
300 mg/dL*
97
95–99/50–90
1328
proteinuria
M3
C/M
Isolated proteinuria,
13.0
50
4.12
95
95–99/50–90
594
chronic kidney disease
stage 3
M4
C/M
Recurrent gross hematuria,
14.5
79
0.72
93
90–95/50–90
1867
acute kidney injury
M5
C/F
Gross hematuria
11.6
79
3.61
61
95–99/50–90
363
M6
C/M
Gross hematuria
11.6
98
255 mg**
74
90–95/95–99
2177
M7
AA/F
Gross hematuria,
10.4
70
3.29
33
50–90/50–90
315
nephrotic syndrome,
acute kidney injury
M8
C/M
Gross hematuria
17.4
67
0.44
94
90–95/50–90
1054
M9
C/M
Recurrent gross hematuria
16.5
100
0.41
76
90–95/50–90
861
M10
AA/M
Recurrent gross hematuria
7.0
102
0.64
90
95–99/50–90
563
M11
AA/F
Gross hematuria
5.5
95
30 mg/dL*
93
50–90/<50
882
M12
C/M
Gross hematuria
8.5
87
0.04
15
50–90/50–90
612
AA: African-American; BMI: body mass index; C: Caucasian; estGFR: estimated glomerular filtration rate; DBP: diastolic blood pressure; SBP: systolic blood pressure.
*Amount of protein by urinary dipstick;
**Amount of protein in 24 hours.
