Effect of an Oral Adsorbent, AST-120, on Dialysis Initiation and Survival in Patients with Chronic Kidney Disease

Table 4

The 12- and 24-month dialysis initiation free rate. The dialysis initiation free rate was significantly higher in the AST-120 group in all the pair-matched patients and also subgroups with or without DM or CVD.

Dialysis initiation free rate (%)	12 months	24 months	𝑃 value
AST-120	25.0	13.7	<0.0001
non-AST-120	10.5	5.7
AST-120, DM(−)	30.1	17.6	<0.0001
non-AST-120, DM(−)	11.2	8.2
AST-120, DM(+)	20.8	10.0	0.0057
non-AST-120, DM(+)	10.8	3.6
AST-120, CVD(−)	24.2	22.6
non-AST-120, CVD(−)	11.2	8.4	0.0063
AST-120, CVD(+)	27.2	12.8
non-AST-120, CVD(+)	9.8	2.9	<0.0001