Achieving Salt Restriction in Chronic Kidney Disease
Table 1
Summary of measures that can be used to estimate sodium intake.
Measure
Objectivity
Burden
Strengths
Limitations
24-hour urinary sodium
Objective
High
(i) Gold standard (ii) Accurately quantifies actual intake when collected correctly
(i) Under/overcollection can introduce error (ii) High participant burden (iii) High cost of analysis (iv) Does not account for daily variation
Spot urinary sodium
Objective
Low
(i) Low participant burden (ii) Quick to collect (iii) Can be used as part of standard practice
(i) Does not account for diurnal variation (ii) Further research needed to determine if valid indicator of daily intake
Open-ended diet history
Self-report
Moderate
(i) Most comprehensive of self-reported measures (ii) Presence of interviewer allows for verification and clarification of information provided (iii) Retrospective nature allows for assessment of “usual intake”
(i) Time consuming to collect and code (ii) Prone to memory lapse and reporting bias (iii) Specialized skills and knowledge of food supply required
24-hour recall
Self-report
Low
(i) Standardized (ii) Can be implemented over the phone (iii) Multiple administrations increases validity (iv) Best for larger population-based studies
(i) Does not account for daily variation in intake (unless repeated) (ii) Prone to reporting bias
Food records (diaries)
Self-report
Depends on number of days
(i) Precise estimation of actual intake on the days where recording occurs, when completed correctly
(i) Subject to participant motivation (ii) Increased number of days increases participant burden (iii) Prone to under-reporting (iv) Prone to modification of intake on days where recording occurs
Food frequency questionnaire
Self-report
Low
(i) Standardized (ii) Quick to administer (iii) Easily coded (iv) Many validation studies
(i) Validity can depend on population in question and food supply. (ii) Subject to memory lapse; inability to summarize intake; false perception of own intake. (iii) Collects information about a limited number of foods (iv) Difficult to measure discretionary salt usage