Review Article

Achieving Salt Restriction in Chronic Kidney Disease

Table 1

Summary of measures that can be used to estimate sodium intake.

MeasureObjectivityBurdenStrengthsLimitations

24-hour urinary sodiumObjectiveHigh(i) Gold standard
(ii) Accurately quantifies actual intake when collected correctly
(i) Under/overcollection can introduce error
(ii) High participant burden
(iii) High cost of analysis
(iv) Does not account for daily variation

Spot urinary sodiumObjectiveLow(i) Low participant burden
(ii) Quick to collect
(iii) Can be used as part of standard practice
(i) Does not account for diurnal variation
(ii) Further research needed to determine if valid indicator of daily intake

Open-ended diet history Self-reportModerate(i) Most comprehensive of self-reported measures
(ii) Presence of interviewer allows for verification and clarification of information provided
(iii) Retrospective nature allows for assessment of “usual intake”
(i) Time consuming to collect and code
(ii) Prone to memory lapse and reporting bias
(iii) Specialized skills and knowledge of food supply required

24-hour recallSelf-reportLow(i) Standardized
(ii) Can be implemented over the phone
(iii) Multiple administrations increases validity
(iv) Best for larger population-based studies
(i) Does not account for daily variation in intake (unless repeated)
(ii) Prone to reporting bias

Food records 
(diaries)
Self-reportDepends on number of days(i) Precise estimation of actual intake on the days where recording occurs, when completed correctly (i) Subject to participant motivation
(ii) Increased number of days increases participant burden
(iii) Prone to under-reporting
(iv) Prone to modification of intake on days where recording occurs

Food frequency questionnaireSelf-reportLow(i) Standardized
(ii) Quick to administer
(iii) Easily coded
(iv) Many validation studies
(i) Validity can depend on population in question and food supply.
(ii) Subject to memory lapse; inability to summarize intake; false perception of own intake.
(iii) Collects information about a limited number of foods
(iv) Difficult to measure discretionary salt usage