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International Journal of Nephrology
Volume 2013, Article ID 424915, 6 pages
Review Article

Bimodal Solutions or Twice-Daily Icodextrin to Enhance Ultrafiltration in Peritoneal Dialysis Patients

1Hemodialysis Unit, Kyanous Stavros Patras, Germanou 115, 26225 Patras, Greece
2Peritoneal Dialysis Program, University Health Network, University of Toronto, ON, Canada

Received 15 August 2012; Accepted 18 December 2012

Academic Editor: Wai-Kei Lo

Copyright © 2013 Periklis Dousdampanis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The efficacy and safety of icodextrin has been well established. In this paper, we will discuss the pharmacokinetics and biocompatibility of icodextrin and its clinical effect on fluid management in peritoneal dialysis patients. Novel strategies for its prescription for peritoneal dialysis patients with inadequate ultrafiltration are reviewed.