International Journal of Nephrology / 2013 / Article / Tab 1

Research Article

Haptoglobin Genotype and Risk Markers of Cardiovascular Disease in Patients with Chronic Kidney Disease

Table 1

Clinical characteristics of patients with haptoglobin genotype 2-2 compared to patients with haptoglobin genotypes 1-1 and 2-1.

Haptoglobin genotypes 1-1 and 2-1 Haptoglobin genotype 2-2
( ) ( )

Age (y)60 ± 1156 ± 13ns
Women ( )18 (45%)2 (13%)0.03
Smoking ( ) 14 (35%)4 (25%)ns
Body mass index (kg/m²)28 ± 530 ± 5ns
Beta-blocker treatment ( )16 (42%)7 (44%)ns
Haemodynamic parameters
 Systolic BP (mmHg)142 ± 18140 ± 18ns
 Diastolic BP (mmHg)78 ± 1080 ± 9ns
 Heart rate (beats per min)72 ± 1077 ± 11ns
Laboratory parameters
 Creatinine clearance (mL/min)35 ±1845 ± 20ns
 Haemoglobin (mmol/L)7.6 ± 18.0 ± 1ns
 Hs-CRP (mg/L)2.5 (0.3; 24.0)6.9 (0.6; 29.7)0.002
HRV indices
 RR (ms)853 ± 124790 ± 113ns
 SDNN (ms)126 ± 37100 ± 270.02
 SDNNindex (ms)45 (39; 51)39 (33; 45)ns
 SDANN (ms)113 ± 3690 ± 280.04
 pNN50 (%)5.5 (3.5; 8.8)3.4 (1.6; 7.1)ns
 RMSSD (ms)24 (20; 30)22 (17; 28)ns

Values are mean ± SD or number of patients (%), except from high-sensitive C-reactive protein and heart rate variability indices SDNNindex, pNN50, and RMSSD which are given in geometric mean and ranges.
Abbreviations: BP: blood pressure, hs-CRP: high-sensitive C-reactive protein, and HRV: heart rate variability.