Acute Renal Failure in Patients with Severe Falciparum Malaria: Using the WHO 2006 and RIFLE Criteria
Table 3
Univariate and multivariate logistic regression analysis of risk factors for in-hospital mortality among severe falciparum malaria patients with acute kidney injury.
Parameters
Univariate analysis
Multivariate analysis*
OR† (95% CI‡)
P value
OR† (95% CI‡)
P value
Glasgow coma scale ≤10
8.477 (3.852–18.654)
<0.001
Number of WHO criteria ≥4
22.500 (7.625–66.396)
<0.001
Inotropic drug
No
1.000
1.000
Dopamine
17.185 (5.945–49.679)
<0.001
7.172 (1.827–28.145)
0.005
Adrenaline
130.500 (34.422–494.744)
<0.001
14.502 (2.874–73.166)
0.001
Mechanical ventilator
37.266 (12.450–111.546)
<0.001
10.806 (2.569–45.459)
0.001
WBC# >12.0 × 109/L
5.286 (2.602–10.736)
<0.001
3.982 (1.146–13.836)
0.030
Potassium >5.5 mmol/L
10.427 (2.731–39.808)
0.001
Bicarbonate <15 mmol/L
6.195 (2.509–15.295)
<0.001
Blood sugar <60 mg/dL
12.000 (1.379–104.410)
0.024
AST€ >500 U/L
7.429 (2.646–20.858)
<0.001
ALT∥ >500 U/L
13.875 (1.497–128.561)
0.021
Albumin ≤2.5 mg/dL
2.597 (1.205–5.597)
0.015
Unaffected factors including the Glasgow coma scale, total WHO criteria, potassium, bicarbonate, blood sugar, ALT∥, and albumin.†OR: odds ratio. ‡CI: confidence intervals. #WBC: white blood cell count. €AST: aspartate aminotransferase. ∥ALT: alanine aminotransferase.
