Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
Table 5
Univariate and multivariate regression analyses demonstrating clinical factors showing correlation with renal pathological chronicity index (CI).
Univariate regression
Multivariate regression = 0.409
Beta
SE.
value
Beta
SE.
value
Age (yrs)
0.01
0.01
0.762
SBP (mmHg)
0.02
0.01
0.001
DBP (mmHg)
0.03
0.01
0.006
Serositis
0.86
0.37
0.020
Anti-dsDNA
0.64
0.38
0.092
0.67
0.30
0.026
Blood urea nitrogen (mg/dL)
0.04
0.01
<0.001
Serum creatinine (mg/dL)
1.17
0.13
<0.001
0.62
0.21
0.004
Estimated GFR (mL/min/1.73 m2)
−0.03
0.00
<0.001
−0.02
0.01
0.008
Hemoglobin (g/dL)
−0.37
0.07
<0.001
−0.20
0.06
0.002
Serum albumin (g/dL)
−0.39
0.22
0.077
UPCR (g/g creatinine)
0.13
0.05
0.005
0.12
0.04
0.003
Microscopic hematuria
−0.58
0.31
0.063
−1.06
0.26
<0.001
Independent variables in the multivariate model were chosen using a stepwise regression analysis where all significant variables listed in the univariate analysis were included. DBP: diastolic blood pressure, GFR: glomerular filtration rate, SBP: systolic blood pressure, and UPCR: urine protein creatinine ratio.
