International Journal of Nephrology / 2016 / Article / Tab 1

Review Article

Prevalence and Risk Factors of Lower Limb Amputation in Patients with End-Stage Renal Failure on Dialysis: A Systematic Review

Table 1

Characteristics of studies that assessed amputation in subjects on renal dialysis.

AuthorCountryTotal casesMean age (y)Male (%)Time on dialysisDMSmokingHTNCADAmputation (%)

Speckman et al., 2004 [19]USA3272 HD53.4%1751 (53.5%)1711 (52.3%)116 (4%)
Locking-Cusolito et al., 2005 [20]Canada232 HD65.1130 (56%)98 (42.2%)75%50%31 (13.4%)
Reddy et al., 2007 [21]USA271 HD70.5 ± 12127 (47%)18 ± 27  (m)176 (65%)37 (14%)244 (90%)146 (54%)34 (13%)
Combe et al., 2009 [22]Multinational29838 HD61.3 ± 1557.7%3.3 ± 5 (y)1112917.7%77.2%41.6%6%
Ishii et al., 2012 [23]Japan1513 HD63 ± 13.566.7%73922.6%74.05%4.4%26 (1.7%)
Plantinga et al., 2009 [24]USA1041 (767 HD, 274 PD)57.9 ± 1554.2%54%60.6%24.5%136 (13%)

HTN, hypertension; CAD, coronary artery disease; DM, diabetes mellitus; HD, haemodialysis; PD, peritoneal dialysis; (y), years; (m), months; USA, Unites States of America.

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