Review Article
Prevalence and Risk Factors of Lower Limb Amputation in Patients with End-Stage Renal Failure on Dialysis: A Systematic Review
Table 1
Characteristics of studies that assessed amputation in subjects on renal dialysis.
| | Author | Country | Total cases | Mean age (y) | Male (%) | Time on dialysis | DM | Smoking | HTN | CAD | Amputation (%) |
| | Speckman et al., 2004 [19] | USA | 3272 HD | — | 53.4% | — | 1751 (53.5%) | — | — | 1711 (52.3%) | 116 (4%) | | Locking-Cusolito et al., 2005 [20] | Canada | 232 HD | 65.1 | 130 (56%) | — | 98 (42.2%) | — | 75% | 50% | 31 (13.4%) | | Reddy et al., 2007 [21] | USA | 271 HD | 70.5 ± 12 | 127 (47%) | 18 ± 27 (m) | 176 (65%) | 37 (14%) | 244 (90%) | 146 (54%) | 34 (13%) | | Combe et al., 2009 [22] | Multinational | 29838 HD | 61.3 ± 15 | 57.7% | 3.3 ± 5 (y) | 11129 | 17.7% | 77.2% | 41.6% | 6% | | Ishii et al., 2012 [23] | Japan | 1513 HD | 63 ± 13.5 | 66.7% | — | 739 | 22.6% | 74.05% | 4.4% | 26 (1.7%) | | Plantinga et al., 2009 [24] | USA | 1041 (767 HD, 274 PD) | 57.9 ± 15 | 54.2% | — | 54% | 60.6% | — | 24.5% | 136 (13%) |
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HTN, hypertension; CAD, coronary artery disease; DM, diabetes mellitus; HD, haemodialysis; PD, peritoneal dialysis; (y), years; (m), months; USA, Unites States of America.
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