Review Article

Acute Kidney Injury in Hematopoietic Stem Cell Transplantation: A Review

Table 2

Incidence and risk factors for different types of HSCT.

Type of transplantIncidence rangeRisk factors

Myeloablative allogeneic transplantation18.8–66%Female sex, hypertension, sepsis, hepatic SOS, GVHD, amphotericin B

Nonmyeloablative allogeneic transplantation29–53.6%Diabetes mellitus, >3 prior lines of chemotherapy, acute GVHD, methotrexate use against GVHD prophylaxis

Myeloablative autologous transplantation12–52%Sepsis, amphotericin B toxicity, aminoglycoside (for sepsis) toxicity

HSCT: hematopoietic stem cell transplantation; Hepatic SOS: sinusoidal obstruction syndrome; GVHD: graft-versus-host disease.