Research Article

Erythropoietin Dose and Mortality in Hemodialysis Patients: Marginal Structural Model to Examine Causality

Table 3

Adjusted odds ratios (95% confidence interval) for mortality by weekly epoetin- doses in overall patient cohort.

Epoetin- (U/wk)All-causeCardiovascularInfectious

<6 000 ReferenceReferenceReference
6 000 to <12 0001.02 (0.94–1.10)1.13 (1.05–1.23)1.12 (1.00–1.25)
12 000 to <18 0001.08 (1.00–1.18)1.21 (1.10–1.32)1.11 (0.98–1.26)
18 000 to <24 0001.17 (1.06–1.28)1.23 (1.12–1.36)1.14 (1.00–1.30)
24 000 to <30 0001.27 (1.15–1.41)1.35 (1.22–1.50)1.13 (0.99–1.29)
≥30 0001.52 (1.37–1.69)1.44 (1.29–1.59)1.28 (1.11–1.48)

Note: bold font indicates statistically significant odds ratios.