Is Anticoagulation Discontinuation Achievable with Citrate Dialysate during HDF Sessions?

Table 2

Nadroparin use and clotting episodes description.

	Months on citrate (number of sessions)	Nadroparin; Dose max (UI)	Nadroparin; Dose min (UI)	Nadroparin; Last dose (UI)	Clotting episodes	VKA	Clopidogrel	Aspirin
Patient 1	3,2 (38)	3800	950	950	1 at 950 UI	No	Yes	Yes
Patient 2	4,5 (58)	4750	0	4750	1 at 0	No	No	Yes
					8–950 to 3800 UI
					1 at 4750 UI
Patient 3	11,7 (139)	2850	0	1900	3 at 0 UI	No	No	Yes
Patient 4	4,1 (55)	2850	0	950	2 at 0 UI	No	No	Yes
Patient 5	2,6 (34)	2850	0	950	3 at 0 UI	No	No	Yes
Patient 6	11,6 (143)	2850	0	1900	2 at 0 UI	No	No	No
					1 at 950 UI
Patient 7	10,2 (126)	3800	0	4750	2 at 0 UI	Yes	No	No
					4–950 to 1900 UI
					1 at 3800
Patient 8	6,8 (88)	1900	950	950	0	Yes	No	No
Patient 9	7 (87)	2850	0	950	1 at 0 UI	No	No	No
					1 at 950 UI
Patient 10	3,0 (41)	3800	2750	2750	1 at 2750 UI	No	No	Yes
Patient 11	5,7 (74)	5700	0	1900	2 at 0	No	No	Yes
					3 at 1900 UI
					1 at 5700 UI
Patient 12	11,3 (144)	2850	0	0	0	Yes	No	No
Patient 13	11,6 (147)	4750	0	0	1 at 0 UI	No	No	Yes
Patient 14	5,2 (58)	1900	0	0	0	Yes	No	Yes
Patient 15	7,1 (88)	3800	0	950	1 at 0 UI	No	No	Yes
Patient 16	3,9 (45)	3800	0	950	2 at 0 UI	No	No	Yes
Patient 17	4,9 (44)	2850	0	950	2 at 0 UI	No	No	Yes
Patient 18	1,8 (23)	4750	3800	4750	9 at 3800 UI	No	No	No
Patient 19	9,5 (120)	1900	0	0	0	Yes	No	Yes
Patient 20	6,8 (76)	3800	950	950	1 at 1900 UI	No	No	No
					3 at 2850 UI
Patient 21	5,2 (68)	7600	4750	5700	1 at 4750 UI	No	No	Yes
					1 at 5700 UI
					1 at 7600 UI
Patient 22	1,9 (17)	5700	950	1900	2 at 950 UI	No	Yes	Yes
					1 at 1900 UI
Patient 23	5 (51)	3800	950	950	1 at 3800 UI	No	Yes	No
					3 at 2850 UI
					1 at 950 UI
Patient 24	11,5 (146)	3800	0	950	3 at 0 UI	No	Yes	No
					2 at 950 UI
Patient 25	2,7 (35)	1900	0	0	0	Yes	No	No
Patient 26	5,8 (73)	2750	1900	2750	1 at 1900 UI	No	Yes	No
					4 at 2750 UI
Patient 27	3,2 (40)	3800	0	1900	1 at 0 UI	No	No	Yes
Patient 28	1,7 (36)	2750	0	950	1 at 0 UI	No	No	No
					1 at 950 UI

No nadroparin during 7.1 months in this patient treated with VKA. When VKA was stopped, circuits clotting occurred resulting in nadroparin restart.