Research Article

R229Q Polymorphism of NPHS2 Gene in Group of Iraqi Children with Steroid-Resistant Nephrotic Syndrome

Table 5

The clinical data and disease progression of 53 children with heterozygous and homozygous polymorphic R229Q.

ParameterHeterozygous GA Homozygous AA value

Age at diagnosis (year ± SD)4.853 ± 3.7775.079 ± 3.1440.814
Male/female16/1020/70.328
Consanguinity21180.244
Family history520.204
Hypertension980.697
Renal insufficiency530.409
Response to steroids
SRNS15110.217
SSNS1116
Renal biopsy
 MC650.920
 FSGS53
 MP11

: NS.