Research Article
Microalbuminuria and Retinopathy among Hypertensive Nondiabetic Patients at a Large Public Outpatient Clinic in Southwestern Uganda
Table 2
Logistic regression analysis of factors associated with retinopathy at Mbarara Regional Referral Hospital, Mbarara, Uganda (
patients).
| Explanatory variables (characteristics) | Univariate analysis | Multivariate analysis | OR | 95% CI | value | OR | 95% CI | value |
| Sex | | | | | | | Male | 1.0 | | | | | | Female | 0.79 | 0.49–1.26 | 0.323 | | | |
| Age | | | | | | | Age < 65 years | 1.0 | | | 1.0 | | | Age > 65 years | 2.52 | 1.63–3.94 | 0.0001 | 3.75 | 2.07–5.39 | 0.0001 |
| Smoking history | | | | | | | Current smoker | | | | | | | Nonsmoker | 1.34 | 0.74–2.45 | 0.336 | | | |
| Exercising | | | | | | | Regular exercise | | | | | | | Irregular/no exercise | 0.95 | 0.55–1.62 | 0.837 | | | |
| Duration of hypertension diagnosis | | | | | | | ≤5 years | | | | | | | >5 years | 4.49 | 2.68–7.49 | 0.0001 | 3.73 | 2.12–6.57 | 0.0001 |
| SBP | | | | | | | ≥140 mmHg | | | | | | | <140 mmHg | 2.78 | 1.69–4.55 | 0.0001 | 3.53 | 1.99–6.24 | 0.0001 |
| DBP | | | | | | | ≥90 mmHg | | | | | | | <90 mmHg | 1.11 | 0.69–1.79 | 0.65 | | | |
| BMI | | | | | | | ≥25 Kg/m2 | 1.0 | | | | | | <25 Kg/m2 | 0.76 | 0.48–1.19 | 0.230 | 0.92 | 0.54–1.56 | 0.75 |
| ACEI | | | | | | | Taking ACEIs | | | | | | | Not taking ACEIs | 1.15 | 0.70–1.89 | 0.58 | | | |
| -blocker | | | | | | | Not Taking -blockers | 1.0 | | | | | | Taking -blockers | 1.88 | 1.17–3.02 | 0.009 | 3.05 | 1.68–5.53 | 0.0001 |
| Calcium blocker | | | | | | | Use calcium blockers | | | | | | | No calcium blockers | 1.65 | 1.02–2.68 | 0.042 | 2.16 | 1.19–3.90 | 0.011 |
| Diuretic | | | | | | | Use diuretics | | | | | | | No diuretics | 2.91 | 1.82–4.66 | 0.0001 | 2.91 | 1.68–5.04 | 0.0001 |
| Microalbuminuria (ACR 30–300 mg/g) | 1.23 | 0.78–1.96 | 0.369 | 1.39 | 0.81–2.40 | 0.225 |
| Proteinuria (ACR > 300 mg/g) | 1.32 | 0.82–2.12 | 0.246 | | | |
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Note. Variables with a value less than 0.25 were then included in the multivariate model. |