International Journal of Nephrology / 2019 / Article / Tab 4

Research Article

Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease

Table 4

Relationship between rs13333226 polymorphisms in the UMOD gene and clinical and demographic features in first-degree relatives.

rs13333226AAAGGGp-value#

N (%)221711
Gender (M/F)8/146/113/80.865
Age, years34 (22-53)29 (20-51)25 (22-41)0.684
Systolic BP, mmHg126 (120-139)135 (119-149)128 (120-132)0.662
Diastolic BP, mmHg76 (72-87)75 (72-89)76 (69-82)0.682
Serum creatinine, µmol/L77 (64-84)76 (66-86)65 (62-92)0.601
CKD-EPI eGFR, ml/min per 1.73 m2118 (82-138)105 (91-137)139 (87-143)0.398
Uric acid, mmol/L0.3 (0.3-0.4)0.3 (0.3-0.4)0.3 (0.2-0.3)0.752
Urine ACR mg/mmol1.2 (0.4-2.9)0.4 (0.0-2.2)2.9 (1.4-4.2)0.225
Log Uromodulin concentration (µg/ml), mean ±SD1.0 ± 1.10.8 ± 1.51.1 ± 1.0

Data given as median (interquartile range) unless specified
P values- #Kruskal-Wallis unless specified; earson’s chi square; tests
Abbreviations: BP, blood pressure; eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; ACR, albumin: creatinine ratio.

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