Effect of a Supervised Peridialytic Exercise Program on Serum Asymmetric Dimethylarginine in Maintenance Hemodialysis Patients
Table 2
Comparison of patients with decreasing/stable S. ADMA to patients with increasing S. ADMA.
Parameter
Decreasing ADMA (N = 13)
Increasing ADMA (N = 31)
Statistical test
value
Sex (male/female)
7/6
15/16
χ2
0.741
Age (years)
48 (36–54)
52 (43–59.5)
MW
0.321
Duration of dialysis (months)
59 (38–95)
46 (29.5–78.5)
MW
0.589
Haemoglobin (gm/dL)
8.78 ± 0.7
8.83 ± 0.8
Independent t-test
0.852
S. urea (mg/dL)
93.46 ± 27.6
108.74 ± 28
Independent t-test
0.109
Kt/V
1.09 ± 0.1
1 ± 0.1
Independent t-test
0.02
S. creatinine (mg/dL)
5.9 (4.8–7.7)
6.2 (5.3–7.55)
MW
0.487
S. calcium (mg/dL)
8.89 ± 0.9
9.14 ± 1.1
Independent t-test
0.452
S. phosphorus (mg/dL)
5.82 ± 1.7
4.97 ± 1.2
Independent t-test
0.122
Ca × Ph product (mg2/dL2)
51.35 ± 15.1
45.42 ± 12.2
Independent t-test
0.225
S. CRP (mg/L)
7.7 (5–16.1)
8.1 (5.1–11.75)
MW
0.911
S. ADMA (ng/mL) before exercise
2750 (2500–7250)
2250 (1525–2500)
MW
0.016
S. ADMA (ng/mL) after exercise
2000 (1250–2500)
4000 (2750–9500)
MW
0.000
Physical activity before exercise (low/moderate)
8/5
29/2
Fisher exact test
0.017
Physical activity before exercise (METs/week)
495 (396–594)
396 (198–792)
MW
0.517
Physical activity after exercise (low/moderate)
6/7
17/14
χ2
0.599
Physical activity after exercise (METs. minutes/week)
675 (576–774)
576 (361.5–972)
MW
0.509
Intradialytic hypotensive episodes
11.31 ± 4.8
15.45 ± 5.6
Independent t-test
0.019
Bacterial infections
0 (0–1)
0 (0–1)
MW
0.232
Unless stated otherwise, laboratory parameters are compared for the initial values (before the exercise program). S: serum, Ca: calcium, Ph: phosphorus, CRP: C-reactive protein, ADMA: asymmetric dimethylarginine, METs: metabolic equivalents, MW: Mann-Whitney test, χ2: chi-square test, significant (). Continuous data are expressed as mean ± standard deviation (if parametric) or median (interquartile range) (if nonparametric).
