Research Article

Effects of Low-Flux and High-Flux Dialysis Membranes on Erythropoietin Responsiveness in Hemodialysis Patients

Table 3

Univariate logistic regression analysis of the erythropoietin resistance index among all studied patients.

ParameterβOR95% CI
LowerUpper

Age (years)−0.010.990.9491.0340.66
Weight (kg)−0.0220.9790.9541.0040.1
BMI (kg/m2)−0.0370.9640.881.0550.425
Hemodialysis vintage (months)0.1171.1240.9791.2910.097
IDWG (kg)−2.0740.1260.0430.371≤0.001
ALT (U/L)−0.0530.9490.8561.0520.316
Serum albumin (g/dL)−3.3970.0330.0030.3480.004
eGFR (ml/min/1.73 m2)0.0191.0190.7041.4750.92
Urea reduction ratio (%)0.0261.0270.981.0750.262
Serum uric acid (mg/dL)0.3411.4070.8842.240.15
Hemoglobin (g/dL)−0.420.6570.4730.9140.013
White blood cells (×103/mm3)0.2341.2630.8841.8050.199
Neutrophil (×103/mm3)0.4291.5350.9342.5240.091
Lymphocyte (×103/mm3)−0.020.980.3292.9170.971
Platelets (×103/mm3)0.0021.0020.9921.0120.742
NLR (%)0.7092.0311.1893.470.01
PLR (%)0.0051.0050.9981.0130.184
Serum cholesterol (mg/dL)0.0151.0150.9981.0320.086
Serum triglycerides (mg/dL)−0.0010.9990.9911.0070.814
Low-density lipoprotein (mg/dL)0.0151.0150.9971.0330.096
High-density lipoprotein (mg/dL)0.031.030.9691.0950.339
Serum calcium (mg/dL)0.0051.0050.5161.9580.989
Serum phosphorus (mg/dL)−0.2370.7890.5331.1680.237
iPTH (pg/dL)0.00011.0001.0010.641
Serum iron (μg/dL)−0.0480.9530.9190.9880.01
Transferrin saturation (%)−0.0260.9740.9281.0230.291
Ferritin (ng/mL)0.0011.00111.0020.021
Serum folate (μg/L)0.0321.0330.9421.1320.494
Serum vitamin B12 (pg/mL)0.0011.0010.9991.0020.409

β: regression coefficient, OR: odds ratio, CI: confidence interval, BMI: body mass index, IDWG: interdialytic weight gain, ALT: alanine transaminase, eGFR: estimated glomerular filtration rate, NLR: neutrophil-to-lymphocyte ratio, PLR: platelet-to-lymphocyte ratio, and iPTH: intact parathyroid hormone.