Table of Contents Author Guidelines Submit a Manuscript
International Journal of Otolaryngology
Volume 2009, Article ID 495186, 4 pages
http://dx.doi.org/10.1155/2009/495186
Clinical Study

Concentrations of H1-Receptor Antagonist in the Human Nasal Mucosa

Department of Otolaryngology, Head and Neck Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Received 5 June 2009; Accepted 16 September 2009

Academic Editor: Fuad Baroody

Copyright © 2009 Kenji Takasaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. Baba, A. Konno, and H. Takenaka, Practical Guideline for the Management of Allergic Rhinitis in Japan-Perennial Rhinitis and Pollinosis, Life Science, Tokyo, Japan, 5th edition, 2005.
  2. H. Yokota, H. Mizuuchi, T. Maki, K. Banno, and T. Sato, “Phase I study of TAU-286—single oral administration in healthy male volunteers,” Journal of Clinical Therapeutics & Medicines, vol. 13, pp. 1137–1153, 1997 (Japanese). View at Google Scholar
  3. J. Bousquet, P. Van Cauwenberge, and N. Khaltaev, “Allergic rhinitis and its impact on asthma,” Journal of Allergy and Clinical Immunology, vol. 108, no. 5, supplement, pp. S147–S334, 2001. View at Google Scholar · View at Scopus
  4. M.-A. Wioland, J. Fleury-Feith, P. Corlieu et al., “CFTR, MDR1, and MRP1 immunolocalization in normal human nasal respiratory mucosa,” Journal of Histochemistry & Cytochemistry, vol. 48, no. 9, pp. 1215–1222, 2000. View at Google Scholar · View at Scopus
  5. P. B. Dinis, M. C. Monteiro, M. L. Martins, N. Silva, and A. Gomes, “Sinus tissue pharmacokinetics after oral administration of amoxicillin/clavulanic acid,” The Laryngoscope, vol. 110, no. 6, pp. 1050–1055, 2000. View at Google Scholar · View at Scopus
  6. P. B. Dinis, M. C. Monteiro, R. Lobato, M. L. Martins, and A. Gomes, “Penetration of cefuroxime into chronically inflamed sinus mucosa,” The Laryngoscope, vol. 109, no. 11, pp. 1841–1847, 1999. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. T. Kusumoto, Y. Sakaguchi, Y. Machara, T. Nakashima, M. Furusawa, and K. Sugimachi, “Comparison of in vitro anticancer chemosensitivity between human squamous cell carcinoma and adenocarcinoma,” Oncology, vol. 49, no. 5, pp. 343–346, 1992. View at Google Scholar · View at Scopus
  8. Y. Abe, S. Ogino, M. Irifune et al., “Histamine content, synthesis and degradation in human nasal mucosa,” Clinical & Experimental Allergy, vol. 23, no. 2, pp. 132–136, 1993. View at Google Scholar · View at Scopus
  9. M. Nakaya, N. Takeuchi, and K. Kondo, “Immunohistochemical localization of histamine receptor subtypes in human inferior turbinates,” Annals of Otology, Rhinology & Laryngology, vol. 113, no. 7, pp. 552–557, 2004. View at Google Scholar · View at Scopus
  10. J. Hilbert, E. Radwanski, R. Weglein et al., “Pharmacokinetics and dose proportionality of loratadine,” Journal of Clinical Pharmacology, vol. 27, no. 9, pp. 694–698, 1987. View at Google Scholar · View at Scopus
  11. F. E. R. Simons, N. A. Silver, X. Gu, and K. J. Simons, “Skin concentrations of H1-receptor antagonists,” Journal of Allergy and Clinical Immunology, vol. 107, no. 3, pp. 526–530, 2001. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. K. Hashiguchi, H. Tang, T. Fujita, K. Suematsu, M. Gotoh, and K. Okubo, “Bepotastine besilate OD tablets suppress nasal symptoms caused by Japanese cedar pollen exposure in an artificial exposure chamber (OHIO Chamber),” Expert Opinion on Pharmacotherapy, vol. 10, no. 4, pp. 523–529, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus