p16, Cyclin D1, and HIF-1α Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy

Table 4

Multivariate Cox regression analysis.

Variable	Disease-free survival
	Hazard ratio	95% CI^*	𝑃 value
Age	1.032	0.981–1.085	0.222
Chemotherapy	0.649	0.195–2.164	0.482
p16	0.096	0.013–0.720	0.023
Cyclin D1	1.087	0.540–2.188	0.814
HIF-1α (nuclear)	1.212	0.945–1.555	0.130

^*Confidence interval.