Review Article

Mucin Production and Mucous Cell Metaplasia in Otitis Media

Figure 6

Mucin chaperones are inducible in cultured mouse middle ear epithelial cells. (a) TFF1, TFF2, and TFF3 are barely detected by reverse transcription polymer chain reaction (RT-PCR) in cultured mouse middle ear epithelial cells and are induced by TNFα and RA for two weeks (TR). (b) TFF3 is induced by TR treatment for two weeks as judged by immunohistochemistry. Ctrl, control; bar = 5 μm.
745325.fig.006a
(a)
745325.fig.006b
(b)