Mucin Production and Mucous Cell Metaplasia in Otitis Media

Figure 8

Id1 induces the proliferation of middle ear epithelial cells ((f), H&E stain) and mucous cells (arrows, (h), AB-PAS stain) compared with empty vector controls ((e), H&E, (g), AB-PAS). Note that the thickening of the middle ear epithelium is increased in Id1-transfected animals ((f), between arrows) compared with empty vector-transfected controls (e).