Research Article

Good Clinical Approach: Delphi Consensus for the Use of Betahistine in Menière’s Disease

Table 8

Results of the Consensus Conference on the adverse effects, safety, and efficacy of betahistine. 1 = absolutely disagree, 2 = disagree, 3 = agree, 4 = more than agree, and 5 = absolutely agree. Consensus was reached when the sum of items 1 and 2 or 3, 4, and 5 reached 66%. Same asterisk convention.

12345

In my experience, the following side effects are more common:

1. Headache21%60%16%3%0%

8119

2. Insomnia26%67%3%4%0%

937

3. Gastric disorders19512811

1090

4. Asthmatic crises16%62%19%3%0%

7822

5. Diarrhea17%61%19%3%0%

7822

6. Sexual dysfunctions33%66%1%0%0%

991

7. Sedation29%48%20%3%0%

7723

You think that the adverse effects of betahistine are:

1. Less than 10%4%5%24%27%40%

991

2. From 10 to 20%31%55%10%3%1%

8614

3. More than 20%51%45%3%0%1%

964