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International Journal of Photoenergy
Volume 2012, Article ID 489713, 5 pages
http://dx.doi.org/10.1155/2012/489713
Research Article

Randomized, Double-Blind, and Placebo-Controlled Clinic Report of Intranasal Low-Intensity Laser Therapy on Vascular Diseases

1Laboratory of Laser Sports Medicine, South China Normal University, Guangzhou 510006, China
2Ministry of Education of China Key Laboratory of Laser Life Science, South China Normal University, Guangzhou 510006, China
3Medicine Department, Shanghai Pudong District Cancer Prevention and Cure Hospital, Pudong District, Shanghai 200126, China

Received 27 January 2012; Revised 21 March 2012; Accepted 27 March 2012

Academic Editor: Rui Duan

Copyright © 2012 Timon Cheng-Yi Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The intranasal low intensity GaInP/AlGaInP diode 650 nm laser therapy (ILGLT) might improve blood lipid and hemorheologic behavior of patients in view of its previous research, but it should be further supported by a randomized, double-blind, and placebo-controlled clinical study. In this paper, 90 patients with coronary heart disease or cerebral infarction were randomly divided into two groups, 60 in the treatment group and 30 in the control group, and were blindly treated with ILGLT at 8.38 and 0 mW/cm2 for 30 min each time once a day ten days each session for two sessions between which there were three days for rest, respectively. Fasting blood lipid such as total cholesterol and low/high-density lipoprotein cholesterol and hemorheologic behavior such as blood viscosity, plasma viscosity, redox viscosity and red blood cell aggregation were assessed before the first treatment and after the two sessions and were found to be significantly improved by ILGLT. It was concluded that ILGLT may improve blood lipid and hemorheologic behavior of patients with coronary heart disease or cerebral infarction.